To coincide with the release of the updated CPIC guidelines for SLCO1B1, ABCG2 and CYP2C9 and statin-associated musculoskeletal symptoms, we have updated the statin pharmacokinetic (PK) pathways. We now have one PK pathway for each individual drug in the guideline and have added details of the specific metabolites as well as the candidate genes and references.
Atorvastatin Pathway, Pharmacokinetics
Fluvastatin Pathway, Pharmacokinetics
Lovastatin Pathway, Pharmacokinetics
Pitavastatin Pathway, Pharmacokinetics
Pravastatin Pathway, Pharmacokinetics
Rosuvastatin Pathway, Pharmacokinetics
Simvastatin Pathway, Pharmacokinetics
Note: If you have visited pathways recently you may need to refresh your browser or empty cookies to see the updated versions. Plus the history log at the bottom of the pathway lets you know if you are seeing the most updated version.
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