Tuesday, January 20, 2015

PharmGKB: an example of Precision Medicine

"21st century businesses will rely on American science, technology, research and development. I want the country that eliminated polio and mapped the human genome to lead a new era of medicine — one that delivers the right treatment at the right time. In some patients with cystic fibrosis, this approach has reversed a disease once thought unstoppable. Tonight, I’m launching a new Precision Medicine Initiative to bring us closer to curing diseases like cancer and diabetes — and to give all of us access to the personalized information we need to keep ourselves and our families healthier." - President Barack Obama January 20, 2015

PharmGKB ibuprofen pathways published in Pharmacogenetics and Genomics

We have published the PharmGKB summary: ibuprofen pathways in the Pharmacogenetics and Genomics Journal. This review summarizes the metabolism and transport of ibuprofen, its mechanism of action and discusses genetic variations affecting the pharmacokinetics, efficacy and toxicity of ibuprofen and their clinical significance.

Find out more...
View our ibuprofen PK and PD pathways on PharmGKB:
Ibuprofen pathway, pharmacokinetics
Ibuprofen pathway, pharmacodynamics

Read our new publication: 
PharmGKB summary: ibuprofen pathways
Pharmacogenet Genomics. 2015 Feb;25(2):96-106.

View all pathways on PharmGKB.

Monday, January 5, 2015

Live from PSB: Phil Bourne from the NIH


PharmGKB is at the Pacific Symposium on Biocomputing (PSB) on the big island of Hawaii.

We will broadcast Phil Bourne's talk on "NIH Big Data from Science to Careers" over the web via the BlueJeans teleconferencing system. There will also be a phone number to dial into for audio only as well.

The talk will be at 2:00 pm HST tomorrow, 1/6/2015.

Instructions for joining the teleconference have been posted to the PSB website.