The 2013 update of the CPIC guidelines for CYP2C19 and clopidogrel dosing is now available online, as an accepted article preview.
This updated guideline refines the recommendations for specific CYP2C19 alleles, with emphasis on the appropriate indication for CYP2C19 genotype-directed antiplatelet therapy, and, an expanded literature review to include recent published evidence.
Read the accepted article preview version:
Clinical PharmacogeneticsImplementation Consortium (CPIC) guidelines for cytochrome P450-2C19 (CYP2C19)genotype and clopidogrel therapy: 2013 Update.
Scott SA, Sangkuhl K, Stein CM, Hulot JS, Mega JL, Roden DM, Klein TE, Sabatine MS, Johnson JA, Shuldiner AR.
Clin Pharmacol Ther. 2013 May 22. doi: 10.1038/clpt.2013.105. [Epub ahead of print]
See excerpts from the guideline update:
Please click here to see excerpts from the guideline update and access downloads of the updated and original article and supplements.
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