Current Curators' Favorite Papers: The review by Alfirevic and Pirmohamed discusses genetic factors associated with drug-induced liver injury with a special focus on HLA gene variation [PMID: 22850601]. Parvez et al. reports that a common SNP on chromosome 4q25, which is associated with atrial fibrillation, modulates response to antiarrhythmic drugs [PMID: 22726630]. Savonarola et al. reviews the role of mutational analysis in anti-cancer targeted therapy [PMID: 22760589].