The PharmGKB Very Important Pharmacogene (VIP) Summary for EGFR provides a concise overview of the role of EGFR as a drug target in the treatment of cancer. Key somatic and germline EGFR polymorphisms associated with drug responsiveness and acquired drug resistance are discussed.
- View the interactive EGFR VIP Summary on PharmGKB
- See FDA and EMA drug labels linked to EGFR
- View EGFR variants associated with drug response and resistance
Read the publication:
PharmGKB summary: very important pharmacogene information for the epidermal growth factor receptor. Hodoglugil U, Carrillo MW, Hebert JM, Karachaliou N, Rosell RC, Altman RB, Klein TE.
Pharmacogenet Genomics. 2013 Aug 18. (Epub ahead of print)