Monday, November 27, 2023

New Fluoropyrimidine Toxicity Variants Reported in DPYS and PPARD

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A recent paper highlights new variants and genes a ssociated with severe fluoropyrimidine-related toxicity in patients who were genotyped as...
Thursday, November 9, 2023

Save the Date: ClinPGx 2024 Meeting

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In collaboration with CPIC , PharmGKB , PharmCAT and PharmVar,  the University of Pennsylvania, Penn Center for Precision Medicine will be h...
Tuesday, September 26, 2023

Frequencies of Pharmacogenomic Alleles across UK Biobank Biogeographic Groups Published

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We are happy to announce the publication of our latest research article in the American Journal of Human Genetics (AJHG), titled “Frequencie...
Monday, September 25, 2023

Disulfiram Pathway published in Pharmacogenetics and Genomics

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Substance abuse disorders are a significant public health cost [PMID: 34453125]. Prescribers have limited choices for pharmaceutical therapi...
Friday, August 18, 2023

Please Take This Survey If Your Site Conducts DPYD Genetic Testing Prior to Fluoropyrimidine Chemotherapy

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Dan Hertz ( DLHertz@med.umich.edu ) and the   DPYD   Implementation Team  are collecting information from sites and clinicians in the USA th...
Thursday, July 13, 2023

New AMP testing recommendations for alleles in CYP3A4 and CYP3A5

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The Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharma...
Wednesday, July 12, 2023

Insights on CYP2C19 and phenoconversion

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Phenoconversion in the PGx context is a drug-drug interaction that impacts a drug metabolizing phenotype such that it mimics the effects of ...