Sunday, August 25, 2013

CYP2C8 VIP published in PG&G

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CYP2C8 is a member of the cytochrome P450 family of drug metabolizing enzymes. It plays a major role in the metabolism of many commonly us...
Wednesday, August 21, 2013

New PharmGKB VIP Summary: NAT2

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N -acetyltransferase enzymes (NAT1 and NAT2) are involved in the metabolism and detoxification of xenobiotics. NAT2 is predominantly express...
Monday, August 19, 2013

Tacrolimus and cyclosporine pathways published

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Tacrolimus and cyclosporine are two immunosuppressants given to solid organ transplant patients to prevent allograft rejection. A PharmGKB s...
Friday, August 16, 2013

PharmGKB PGx summaries now available in the Genetic Testing Registry

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The Genetic Testing Registry ( GTR ) now contains summaries written by PharmGKB Curators regarding the association between genes and drug re...
Tuesday, August 13, 2013

Visualizing Levels of Evidence

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PharmGKB Clinical Annotations provide a summary of an association between a genetic variant and a drug response. Each is assigned a level o...
Sunday, August 11, 2013

CPIC guidelines now posted on guidelines.gov

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Six CPIC PGx-based dosing guidelines are now available on the National Guideline Clearinghouse website, a public resource for evidence-ba...
Thursday, August 8, 2013

"Jack of all trades" drug pathway published

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Methylene blue has many clinical uses including the treatment of methemoglobinemia and malaria, as a diagnostic dye and even has potential ...