Thursday, January 31, 2013

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We have updated the pathway: Tamoxifen PK pathway . Tamoxifen is a selective estrogen receptor modulator. It is used to treat estrogen re...
Tuesday, January 29, 2013

Personalized Medicine World Conference 2013

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PharmGKB curators attended the PMWC this week, featuring talks covering different areas and aspects of personalized medicine, including pha...
Tuesday, January 22, 2013

CPIC guidelines for TPMT and Thiopurine dosing: Update 2013

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The 2013 update of the CPIC guidelines for TPMT and Thiopurine dosing is now available online, as an accepted article preview. CPIC genoty...
Friday, January 11, 2013

Additional EMA drug labels released on PharmGKB

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Our collection of drug labels containing pgx information from the European Medicines Agency has been extended: Boceprevir and IL28 Brent...
Wednesday, January 9, 2013

Tailored therapy in asthma? ADRB2 genotype in the context of salmeterol therapy

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In a recent trial, asthmatic children homozygous for the beta2-adrenergic receptor Arg16 variant ( ADRB2 gene, rs1042713 genotype AA) were...
Wednesday, December 19, 2012

CP&T Issue Focuses on Personalized Medicine

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The October 2012 issue of Clinical Pharmacology & Therapeutics focuses on individualized medicine including articles that discuss, revea...
Thursday, December 13, 2012

CPIC publishes guidelines on interpreting genetic test results for HLA-B*5801 when prescribing allopurinol therapy.

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Allopurinol is an analog of the purine base hypoxanthine. It inhibits the conversion of hypoxanthine and xanthine to uric acid by XDH an...